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Dosimetry and Clinical Efficacy of Transcranial Photobiomodulation for Major Depression Disorder: Could they Guide Dosimetry for Alzheimer's Disease?

Background: Major depressive disorder (MDD) is prevalent and has significant impact on individuals and society. Cognitive symptoms are frequent in MDD...
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Transcranial Photobiomodulation (tPBM) for Major Depressive Disorder

Major depressive disorder (MDD) is a leading cause of disability worldwide with current FDA approved treatments often not providing sustained...
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Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression

Mood disorders are associated with elevated inflammation, and the reduction of symptoms after multiple treatments is often accompanied by pro-inflammation...
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Photobiomodulation for Major Depressive Disorder: Linking Transcranial Infrared Light, Biophotons and Oxidative Stress

Incompletely treated major depressive disorder (MDD) poses an enormous global health burden. Conventional treatment for MDD consists of pharmacotherapy and...
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Efficacy of Transcranial Photobiomodulation on Depressive Symptoms: A Meta-Analysis

Background: Transcranial photobiomodulation (tPBM) is a novel, noninvasive, device-based intervention, which has been tested as a possible treatment for various neurological...
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[Near-infrared light therapy ameliorates depression-induced intestinal dysfunction in rats possibly by activating PGC-1 α/Nrf2 signaling and increasing hippocampal BDNF expression]

Objective: To investigate the effect of near-infrared (NIR) light therapy on depression-induced intestinal dysfunction in rats and explore the possible mechanism....
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A Brief Review of Low-Level Light Therapy in Depression Disorder

Introduction: Low-level laser therapy (LLLT), also called Photobiomodulation, has gained widespread acceptance as a mainstream modality, particularly in the form of...
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Efficacy of transcranial photobiomodulation in the treatment for major depressive disorder: A TMS-EEG and pilot study

Background: Major depressive disorder (MDD) was a prevalent mental condition that may be accompanied by decreased excitability of left frontal pole...
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Changes in Brain Function and Structure After Self-Administered Home Photobiomodulation Treatment in a Concussion Case

Traumatic brain injury (TBI) is a common neurological disorder among athletes. Although there are no widely accepted treatments for TBI,...
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A Randomized, Double-Blind, Placebo-Controlled Clinical Trial Evaluating Transcranial Photobiomodulation as Treatment for Concussion

Introduction: Literature indicating that transcranial photobiomodulation (tPBM) may enable the brain to recover normal function after concussion, resulting in symptoms reduction,...
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Low-level light therapy improves cortical metabolic capacity and memory retention

Cerebral hypometabolism characterizes mild cognitive impairment and Alzheimer's disease. Low-level light therapy (LLLT) enhances the metabolic capacity of neurons in...
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Transcranial infrared laser stimulation produces beneficial cognitive and emotional effects in humans

This is the first controlled study demonstrating the beneficial effects of transcranial laser stimulation on cognitive and emotional functions in...
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