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Review of transcranial photobiomodulation for major depressive disorder: targeting brain metabolism, inflammation, oxidative stress, and neurogenesis

We examined the use of near-infrared and red radiation (photobiomodulation, PBM) for treating major depressive disorder (MDD). While still experimental,...
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The potential of transcranial photobiomodulation therapy for treatment of major depressive disorder

Major depressive disorder is a common debilitating mood disorder that affects quality of life. Prefrontal cortex abnormalities, an imbalance in...
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Multi-Watt Near-Infrared Phototherapy for the Treatment of Comorbid Depression: An Open-Label Single-Arm Study

Background: The treatment of depression has been hampered by low efficacy of antidepressant medications and safety concerns with alternative modalities. Recent...
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A case control series for the effect of photobiomodulation in patients with low back pain and concurrent depression

Background and aims: To present incidental findings in patients with low back pain (LBP) who received photobiomodulation (PBM) administered to the...
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Transcranial and systemic photobiomodulation for major depressive disorder: A systematic review of efficacy, tolerability and biological mechanisms

Background: Photobiomodulation (PBM) with red and near-infrared light (NIR) -also known as Low-Level Light Therapy-is a low risk, inexpensive treatment-based on...
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Transcranial photobiomodulation prevents anxiety and depression via changing serotonin and nitric oxide levels in brain of depression model mice: A study of three different doses of 810 nm laser

Objectives: The effectiveness of transcranial photobiomodulation (TPBM) in treating anxiety and depression disorders is a demonstrated and identified issue. However, the...
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Near-infrared photobiomodulation combined with coenzyme Q10 for depression in a mouse model of restraint stress: reduction in oxidative stress, neuroinflammation, and apoptosis

This study was aimed to evaluate the effects of near-infrared (NIR) photobiomodulation (PBM) combined with coenzyme Q10 (CoQ10) on depressive-like behavior,...
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Transcranial Photobiomodulation For The Management Of Depression: Current Perspectives

Major depressive disorder (MDD) is a prevalent condition associated with high rates of disability, as well as suicidal ideation and...
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Study of transcranial photobiomodulation at 945-nm wavelength: anxiety and depression

Transcranial photobiomodulation is an innovative method for the stimulation of neural activity which consists of the exposure of neural tissue...
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Photobiomodulation Therapy Attenuates Anxious-Depressive-Like Behavior in the TgF344 Rat Model

Background: Anxious-depressive-like behavior has been recognized as an early endophenotype in Alzheimer's disease (AD). Recent studies support early treatment of anxious-depressive-like...
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Antidepressant and antioxidant effects of transcranial irradiation with 830-nm low-power laser in an animal model of depression

The present study aimed at investigating the antidepressant and antioxidant actions of near-infrared (NIR) laser at a wavelength of 830...
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Synergistic effects of combined therapy with transcranial photobiomodulation and enriched environment on depressive- and anxiety-like behaviors in a mice model of noise stress

The development of anxiety and depression due to chronic exposure to noise stress has remained as an unsolved health problem...
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