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Study of the NIR Light Induced Effects on Neuroblastoma N2A Cells with Parkinson's-Like Features

Parkinson's disease is an incurable neurodegenerative disorder associated with losses of dopaminergic neurones. The underlying causes of this loss are...
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Near-infrared light (670 nm) reduces MPTP-induced parkinsonism within a broad therapeutic time window

We have shown previously that near-infrared light (NIr), when applied at the same time as a parkinsonian insult (e.g. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine;...
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The behavioural and neuroprotective outcomes when 670nm and 810nm near infrared light are applied together in MPTP-treated mice

We have shown previously that when applied separately, 670nm and 810nm near infrared light (NIr) reduces behavioural deficits and offers...
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Photobiomodulation-induced changes in a monkey model of Parkinson's disease: changes in tyrosine hydroxylase cells and GDNF expression in the striatum

Intracranial application of red to infrared light, known also as photobiomodulation (PBM), has been shown to improve locomotor activity and...
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Remote tissue conditioning is neuroprotective against MPTP insult in mice

leaving a need for treatments that mitigate disease progression. One emerging neuroprotective strategy is remote tissue conditioning, in which mild...
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Photoactivation of ERK/CREB/VMAT2 pathway attenuates MPP+-induced neuronal injury in a cellular model of Parkinson's disease

The vesicular monoamine transporter 2 (VMAT2) pumps dopamine from cytoplasm into synaptic vesicles for subsequent release, and the deficits of...
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Evidence for encephalopsin immunoreactivity in interneurones and striosomes of the monkey striatum

In this study, we examined the cellular distribution of encephalopsin (opsin 3; OPN3) expression in the striatum of non-human primates....
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Photobiomodulation reduces gliosis in the basal ganglia of aged mice

This study explored the effects of long-term photobiomodulation (PBM) on the glial and neuronal organization in the striatum of aged...
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Photobiomodulation in Parkinson's disease: A randomized controlled trial

Transcranial photobiomodulation (PBM), which involves the application of low-intensity red to near-infrared light (600-1100 nm) to the head, provides neuroprotection...
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Parkinson's disease and light: The bright and the Dark sides

Light exerts a major influence on human behaviour and health, mainly owing to the importance of sight in our lives,...
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Effect of Photobiomodulation in Rescuing Lipopolysaccharide-Induced Dopaminergic Cell Loss in the Male Sprague-Dawley Rat

Photobiomodulation (PBM) provides neuroprotection against dopaminergic cell death and associated motor deficits in rodent and primate models of Parkinson's disease...
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Photobiomodulation Mitigates Cerebrovascular Leakage Induced by the Parkinsonian Neurotoxin MPTP

The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is commonly used to model Parkinson's disease (PD) as it specifically damages the nigrostriatal dopaminergic pathway....
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