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Combined effect of recombinant human bone morphogenetic protein-2 and low level laser irradiation on bisphosphonate-treated osteoblasts

Abstract Objectives: The purpose of this study was to evaluate the synergic effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) and...
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The effects of photobiomodulation therapy on mouse pre-osteoblast cell line MC3T3-E1 proliferation and apoptosis via miR-503/Wnt3a pathway

Abstract Photobiomodulation therapy (PBMT) has been demonstrated as regulating osteoblast proliferation. MicroRNAs (miRNAs) are involved in various pathophysiologic processes in...
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The Effects of Photobiomodulation on MC3T3-E1 Cells via 630 nm and 810 nm Light-Emitting Diode

Abstract BACKGROUND Photobiomodulation (PBM) has been explored as a promising therapeutic strategy to regulate bone cell growth; however, the effects...
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Photobiomodulation of human osteoblast-like cells in vitro by low-intensity-pulsed LED light

Abstract Visible light irradiation is an emerging area in regenerative medicine research. We hypothesized that low-intensity-pulsed LED light irradiance may...
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Laser and LED photobiomodulation effects in osteogenic or regular medium on rat calvaria osteoblasts obtained by newly forming bone technique

Abstract The purposes of this study are to evaluate the effects of photobiomodulation (PBM) with laser and LED on rat...
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Effects of Low-Level Er:YAG Laser Irradiation on Proliferation and Calcification of Primary Osteoblast-Like Cells Isolated From Rat Calvaria

Abstract Several reports have shown that the photo-bio-modulation of cells by various lasers has favorable biological effects. However, the effects...
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The Signalling Effects of Photobiomodulation on Osteoblast Proliferation, Maturation and Differentiation: A Review

Abstract Proliferation of osteoblasts is essential for maturation and mineralization of bone matrix. Ossification, the natural phase of bone-forming and...
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Photobiomodulation with a 645 nm Diode Laser of Saos-2 Cells and Platelet-Rich Plasma: The Potential for a New Mechanism of Action

Abstract Objective: The main focus of this in vitro study was to highlight possible differences between outcomes of photobiomodulation performed in the presence...
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Recovering the osteoblastic differentiation potential of mesenchymal stem cells derived from diabetic rats by photobiomodulation therapy

Abstract Autologous cell-based therapy for bone regeneration might be impaired by diabetes mellitus (DM) due to the negative effects on...
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Effects of photobiomodulation on bone remodeling in an osteoblast-osteoclast co-culture system

Abstract The general bone anabolic effect of photobiomodulation (PBM) is largely accepted. As a result, PBM therapy is expected to...
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Photobiomodulation by Near-Infrared 980-nm Wavelengths Regulates Pre-Osteoblast Proliferation and Viability through the PI3K/Akt/Bcl-2 Pathway

Abstract Background: bone tissue regeneration remains a current challenge. A growing body of evidence shows that mitochondrial dysfunction impairs osteogenesis and...
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Bioenergetics of photobiomodulated osteoblast mitochondrial cells derived from human pulp stem cells: systematic review

Abstract Dental pulp cells are a source of multipotent mesenchymal stem cells with a high proliferation rate and multilineage differentiation...
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