Systemic effects of LLLT on bone repair around PLLA-PGA screws in the rabbit tibia

To evaluate the systemic effects of low level laser therapy (LLLT) on the early stages of bone repair after implantation of poly-L-lactic/polyglycolic acid (PLLA-PGA) screws 24 rabbits were randomly allocated to one of two groups, experiment or control. Each animal underwent implantation of one 5 × 1.5 mm PLLA-PGA screw in each tibia (right and left). The experiment group received infrared laser irradiation (830 nm, 4 J, 100 mW, 10.1 s) over the right paw immediately after implantation and every 48 h thereafter, for a maximum of seven sessions. The control group was not irradiated. Both groups were divided into three subgroups according to the observation period (5, 15, or 30 days), after which animals were euthanized.